Research

Alzheimer's blood test

An Alzheimer's blood test measures proteins in blood that reflect the amyloid and tau changes of the disease. It is far easier than a lumbar puncture or PET scan, which is why interest is high, but it is used as part of an assessment in people with symptoms rather than as a screening test for everyone.

Quick answer

An Alzheimer's blood test measures proteins in blood that reflect the amyloid and tau changes of the disease. It is far easier than a lumbar puncture or PET scan, which is why interest is high, but it is used as part of an assessment in people with symptoms rather than as a screening test for everyone.

Why a blood test is a meaningful change

Until recently, confirming the biology of Alzheimer's disease meant a lumbar puncture or specialised PET imaging. Both work; neither is easy to arrange or comfortable to undergo. A blood sample is ordinary, repeatable and available anywhere a laboratory is, which is why this area has moved quickly.

What it can and cannot tell you

These tests estimate the likelihood that amyloid-related change is present. They do not measure how impaired you are, they do not predict when symptoms will appear, and they do not by themselves establish a diagnosis. Nor do they exclude the many other causes of memory difficulty, which is why a normal result still needs the rest of the assessment.

Who it is for

The reasonable use is in someone with cognitive symptoms where confirming or excluding Alzheimer's biology would change what happens next: treatment decisions, planning, or eligibility for research. Testing people without symptoms raises questions that current evidence does not answer well, and it is not offered as a general screen.

About this practice

Clinical Neurology Specialists has been physician-owned since 1998, when Leo Germin, M.D., FAANEM founded it. Five board-certified neurologists and four advanced practice providers see patients at the Las Vegas and Henderson offices, each with its own AANEM-accredited electrodiagnostic laboratory.

Clinical Neurology Specialists is an adult outpatient neurology practice for patients 18 and older. The practice performs no surgery and operates no imaging suite, infusion suite or interventional pain programme, and provides no emergency or inpatient care.

MRI, CT, carotid ultrasound and lumbar puncture are not performed at these offices. They are arranged at an imaging centre or hospital, and the report is reviewed with you by the neurologist who ordered it.

Emergency & crisis resources: Clinical Neurology Specialists is not an emergency service. For stroke symptoms, a seizure lasting more than five minutes or any medical emergency, call 911 or go to the nearest emergency room. For a mental health crisis, call or text 988 (Suicide & Crisis Lifeline).

Frequently asked

Questions about alzheimer's blood test

What is an Alzheimer's blood test?
A blood test that measures proteins reflecting the amyloid and tau changes associated with Alzheimer's disease. It offers a much simpler route to that information than cerebrospinal fluid analysis or PET imaging. It is used within an assessment of someone who already has symptoms, rather than as a screening test for the general population. The order is written here and the sample is collected at a laboratory.
How is it used in the assessment at CNS?
As one input among several. The assessment starts with history, an account from someone close to you, a cognitive evaluation and a search for reversible causes. Where biomarker information would change the plan, it is arranged and then interpreted alongside everything else.
Should I get one if I am just worried about my memory?
Discuss the worry first. Many memory complaints have causes that are treatable and unrelated to Alzheimer's disease, including sleep apnoea, thyroid problems, vitamin deficiency, depression and medication effects. Those are worth excluding before reaching for a biomarker. Start with the assessment rather than the test. If a reversible cause is found, that is a far better outcome than a biomarker result.
Is it accurate?
Performance varies between the available tests and depends on who is being tested. They are considerably more informative in people with symptoms than in people without. This is an area where the evidence is still developing, and any honest answer includes that caveat.
Is the blood draw done at CNS?
The order is written here; the sample is collected at a laboratory. These offices have no imaging suite and do not perform lumbar puncture or PET, so those routes are arranged externally when they are the right choice. What happens at these offices is the clinical assessment and the interpretation of whatever the external test returns.

Physician-reviewed. Reviewed by the physicians of Clinical Neurology Specialists — board-certified neurologists, AANEM-accredited electrodiagnostic laboratories, physician-owned since 1998. Reviewed 1 August 2026. This article is general education for adults 18 and older and is not a substitute for a consultation.

Next step

Speak to a board-certified neurologist

Adults 18 and older, at the Las Vegas and Henderson offices. Call 702-804-1212 or request an appointment online.