Research

Alzheimer's prevention study

An Alzheimer's prevention study tests whether a treatment can delay or prevent cognitive decline in people who do not yet have dementia. Participants are usually identified by risk factors or biomarker status rather than by symptoms. CNS is a research partner of the GAP Foundation.

Quick answer

An Alzheimer's prevention study tests whether a treatment can delay or prevent cognitive decline in people who do not yet have dementia. Participants are usually identified by risk factors or biomarker status rather than by symptoms. CNS is a research partner of the GAP Foundation.

How prevention studies differ

A treatment study enrols people who already have symptoms and asks whether they improve. A prevention study enrols people who do not, and asks whether the outcome can be avoided or delayed. That makes them longer, larger and dependent on carefully defined entry criteria, often involving biomarker status or family history rather than complaints.

What taking part usually involves

Screening to confirm eligibility, which may include cognitive testing, blood work and sometimes imaging. Then scheduled visits over an extended period with repeated assessments. Some studies involve a placebo group, meaning you may not receive the active treatment. All of this is explained in the consent process before you commit.

Deciding whether it is for you

Participation is voluntary and entirely separate from your clinical care; declining changes nothing about the treatment you receive. Reasonable questions include the time commitment, what happens if you withdraw, whether results are shared with you, and what the placebo chance is. CNS performs no infusions on site, so studies requiring them are conducted elsewhere. One practical point often missed: prevention studies frequently need a study partner, someone who knows you well and can attend some visits and answer questions about changes they have noticed. Ask early whether that is required, because finding somebody willing to commit for the duration is harder than it sounds and is a common reason people withdraw part-way through.

About this practice

Clinical Neurology Specialists has been physician-owned since 1998, when Leo Germin, M.D., FAANEM founded it. Five board-certified neurologists and four advanced practice providers see patients at the Las Vegas and Henderson offices, each with its own AANEM-accredited electrodiagnostic laboratory.

Clinical Neurology Specialists is an adult outpatient neurology practice for patients 18 and older. The practice performs no surgery and operates no imaging suite, infusion suite or interventional pain programme, and provides no emergency or inpatient care.

Emergency & crisis resources: Clinical Neurology Specialists is not an emergency service. For stroke symptoms, a seizure lasting more than five minutes or any medical emergency, call 911 or go to the nearest emergency room. For a mental health crisis, call or text 988 (Suicide & Crisis Lifeline).

Frequently asked

Questions about alzheimer's prevention study

What is an Alzheimer's prevention study?
A clinical study testing whether a treatment can delay or prevent cognitive decline in people who do not yet have dementia. Eligibility is usually based on risk factors or biomarker status rather than existing symptoms. Because the outcome being prevented takes years to appear, these studies run longer and ask more of participants than treatment studies do.
Is CNS involved in Alzheimer's research?
Yes. The practice is a research partner of the GAP Foundation. Whether any individual is eligible for a specific study depends on that study's criteria and is discussed case by case rather than assumed. Studies requiring infusions are conducted elsewhere, since these offices have no infusion suite, though the clinical relationship continues here.
Do I have to take part to be treated here?
No. Research participation is entirely voluntary and separate from clinical care. Declining, or withdrawing later, changes nothing about the treatment you receive. You can also withdraw at any point after joining without giving a reason and without any effect on your care. That is a standard protection, not a courtesy, and it should be stated plainly in the consent documents you are given.
What questions should I ask before joining?
The time commitment and number of visits, whether there is a placebo group and what the chance of receiving it is, what happens if you withdraw, whether your individual results are shared with you, and who to contact with concerns.
Can I join if I already have memory symptoms?
Possibly, but not a prevention study, which by design enrols people without dementia. There may be other studies appropriate to your situation. That is a conversation for the clinical appointment. Bring the question to your appointment, since eligibility depends on specifics that cannot be judged from a web page and criteria change as studies open and close.

Physician-reviewed. Reviewed by the physicians of Clinical Neurology Specialists — board-certified neurologists, AANEM-accredited electrodiagnostic laboratories, physician-owned since 1998. Reviewed 1 August 2026. This article is general education for adults 18 and older and is not a substitute for a consultation.

Next step

Speak to a board-certified neurologist

Adults 18 and older, at the Las Vegas and Henderson offices. Call 702-804-1212 or request an appointment online.