Conditions

Medications for multiple sclerosis

MS medications fall into three groups: disease-modifying therapies that reduce relapses and disability accumulation, short courses of steroids for acute relapses, and separate treatments for individual symptoms such as fatigue, spasticity and bladder problems. Symptom treatments are managed separately from disease-modifying therapy, so bringing a written list matters because appointments naturally focus on relapses.

Quick answer

MS medications fall into three groups: disease-modifying therapies that reduce relapses and disability accumulation, short courses of steroids for acute relapses, and separate treatments for individual symptoms such as fatigue, spasticity and bladder problems. Symptom treatments are managed separately from disease-modifying therapy, so bringing a written list matters because appointments naturally focus on relapses.

Disease-modifying therapy

These reduce relapse frequency and slow accumulation of disability, and they are the central long-term treatment. They come as injections, tablets and infusions, and range from moderately effective with well-established safety records to highly effective with more monitoring required. Choice weighs how active your MS is, your risk tolerance, monitoring practicalities, pregnancy plans and your own preferences. This practice operates no infusion suite, so infusion-based therapies are arranged elsewhere while neurological care continues here.

Treating a relapse, and what does not need treating

Acute relapses are treated with a short course of high-dose corticosteroids, which speeds recovery from the relapse without changing the long-term course. Not every worsening is a relapse: heat, infection, fatigue and stress can all temporarily worsen symptoms without new inflammation, and treating those with steroids helps nobody. In this climate heat effects are a particularly common cause of apparent worsening, and they resolve on cooling.

Symptom treatments, managed separately

Fatigue, spasticity, bladder dysfunction, neuropathic pain, tremor, walking difficulty and mood each have their own treatments and are managed alongside disease-modifying therapy rather than by it. This matters because appointments naturally focus on relapses and DMTs, so symptoms go unraised. Bring a written list. Bladder symptoms in particular are under-reported and very treatable, and describing which type you have changes what is prescribed.

About this practice

Clinical Neurology Specialists has been physician-owned since 1998, when Leo Germin, M.D., FAANEM founded it. Five board-certified neurologists and four advanced practice providers see patients at the Las Vegas and Henderson offices, each with its own AANEM-accredited electrodiagnostic laboratory.

Clinical Neurology Specialists is an adult outpatient neurology practice for patients 18 and older. The practice performs no surgery and operates no imaging suite, infusion suite or interventional pain programme, and provides no emergency or inpatient care.

Emergency & crisis resources: Clinical Neurology Specialists is not an emergency service. For stroke symptoms, a seizure lasting more than five minutes or any medical emergency, call 911 or go to the nearest emergency room. For a mental health crisis, call or text 988 (Suicide & Crisis Lifeline).

Frequently asked

Questions about medications for multiple sclerosis

What medications are used for multiple sclerosis?
Three groups: disease-modifying therapies that reduce relapses and slow disability, given as injections, tablets or infusions; short high-dose corticosteroid courses for acute relapses; and separate treatments for individual symptoms such as fatigue, spasticity and bladder problems. This practice operates no infusion suite, so infusion-based therapies are arranged elsewhere while neurological care continues here.
How is a disease-modifying therapy chosen?
By weighing how active your MS is, your risk tolerance, what monitoring each requires, pregnancy plans and your own preferences. Options range from moderately effective with long safety records to highly effective with more intensive monitoring, so there is a real trade-off to discuss. It is a genuine shared decision rather than a single obvious answer, so it is worth asking what the alternatives were and why this one was suggested.
Do steroids change the course of MS?
No. A short high-dose course speeds recovery from an acute relapse but does not alter the long-term course. That is what disease-modifying therapy is for, which is why steroids are used episodically rather than continuously. Using them repeatedly for symptoms that are not relapses achieves nothing and carries real cumulative risks, which is why distinguishing the two matters.
Is every worsening a relapse?
No, and this matters. Heat, infection, fatigue and stress can all temporarily worsen symptoms without new inflammation, and steroids do not help those. In this climate heat is a particularly common cause, and those effects resolve on cooling rather than persisting. Reporting new symptoms that last more than a day and do not settle with cooling is the practical rule, rather than trying to judge the cause yourself.
Can I have infusion therapy at CNS?
No. This practice operates no infusion suite, so infusion-based disease-modifying therapies are arranged at an appropriate centre. Neurological assessment, monitoring and symptom management continue here alongside that. Neurological assessment, relapse management, symptom treatment and monitoring all continue here alongside whatever the infusion centre provides, so a referral for infusion is not a transfer of your overall care to somebody else.

Physician-reviewed. Reviewed by the physicians of Clinical Neurology Specialists — board-certified neurologists, AANEM-accredited electrodiagnostic laboratories, physician-owned since 1998. Reviewed 1 August 2026. This article is general education for adults 18 and older and is not a substitute for a consultation.

Next step

Speak to a board-certified neurologist

Adults 18 and older, at the Las Vegas and Henderson offices. Call 702-804-1212 or request an appointment online.